@article {57989,
	title = {Latency represents sound frequency in mouse IC},
	journal = {Science in China Series C: Life Sciences},
	volume = {50},
	year = {2007},
	month = {Jan-04-2007},
	pages = {258 - 264},
	abstract = {<p>Frequency is one of the fundamental parameters of sound. The frequency of an acoustic stimulus can be represented by a neural response such as spike rate, and/or first spike latency (FSL) of a given neuron. The spike rates/frequency function of most neurons changes with different acoustic amplitudes, whereas FSL/frequency function is highly stable. This implies that FSL might represent the frequency of a sound stimulus more efficiently than spike rate. This study involved representations of acoustic frequency by spike rate and FSL of central inferior colliculus (IC) neurons responding to free-field pure-tone stimuli. We found that the FSLs of neurons responding to characteristic frequency (CF) of sound stimulus were usually the shortest, regardless of sound intensity, and that spike rates of most neurons showed a variety of function according to sound frequency, especially at high intensities. These results strongly suggest that FSL of auditory IC neurons can represent sound frequency more precisely than spike rate.</p>
},
	keywords = {characteristic frequency, first spike latency, inferior colliculus, mouse, representation},
	issn = {1006-9305},
	doi = {10.1007/s11427-007-0020-6},
	url = {http://link.springer.com/10.1007/s11427-007-0020-6},
	author = {Qiu, Qiang and Tang, Jie and Yu, ZuLin and Zhang, Juan and Zhou, YingJie and Xiao, ZhongJu and Shen, JunXian}
}
